The college takes its roots from the establishment of Agusan Agricultural High School (AAHS) in 1918 thru the passage of an Omnibus Bill filed by Honorable Elisa Rosales Ochoa, First Congresswoman of the Philippines. The school was later converted into Northern Mindanao Agricultural College (NORMINAC) on June 22, 1963, through the Republic Act No. 3604.
As Caraga Region rapidly grew and developed in both agricultural and industrial sectors, House Bill No. 25 was passed by the then Assemblyman Antonio R. Tupaz, converting NORMINAC to the Northern Mindanao State Institute of Science and Technology (NORMISIST). The House Bill became Batas Pambansa Blg. 241 when President Ferdinand Marcos signed it into law on November 11, 1982, and NORMINAC officially became NORMISIST.
In 1987, a two-storey structure was built as one of the main academic buildings of NORMISIST. It has a total area of 1,300 sq. m. or 12 classrooms and an average capacity of 720 people. This structure later became home to the College of Agriculture and Natural Resources or CASNR.
As part of its commitment to serve larger academic areas of responsibility, and with the integration of a CHED supervised school, NORMISIST has evolved into a system with CASNR as one of its colleges.
Through House Bill No. 5110 and Republic Act No. 9854, NORMISIST officially became Caraga State University (CSU) on December 16, 2009. At that time, CASNR had also witnessed growth among its enrollees on five undergraduate and one graduate program offerings.
On December 8, 2017, CASNR was reorganized due to the separation of the Department of Natural Resources to establish the College of Forestry and Environmental Science (CoFES). On May 30, 2018, through BOR Resolution No. 39-05, s. 2018, CASNR with one remaining department (Department of Agricultural Sciences) was restructured into the present-day College of Agriculture and Agri-Industries (CAA).
Through the years, the college maintained its resilience by adhering to its goal, “to produce competent professionals, technologists, and entrepreneurs in agriculture and related fields” and also silently adapting to changes that occur in the university and modern-day society. Further, with the addition of young, intelligent, active, and visionary faculty members, CAA envisions to excel on the disciplines it covers through the adoption of new technologies and application of integrated methods in instruction, research, and extension of agricultural science and technology.